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Saturday, April 30, 2016

There is a fine line between tolerance and death


This really breaks my heart. I feel like I grew up under his Purple glory. Prince's death was probably an accidental overdose.

With these drugs, the difference between tolerance and death is a fine line. Rebound pain is a symptom I see frequently with opiate use. When the levels of the opiate drops in the blood, the dependent brain senses the drop and creates symptoms to get what it thinks it needs. These symptoms are "flu like" with increasing pain. The brain creates and escalates pain to get more drug. Rebound pain is a common cause of accidental overdose.

The treatment is to detox off opiate meds to extinguish the rebound effect and treat the underlying cause of pain--here possibly minimally invasive hip surgery. Also motivational psychotherapy to minimize tolerance in the future, is tremendously helpful.